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Corresponding Author
Ibnu Susanto Joyosemito
Institutions
1 University of Bhayangkara Jakarta Raya, Faculty of Engineering, Environmental Engineering, Jakarta, Indonesia
2 Syarif Hidayatullah State Islamic University, Faculty of Medicine and Health Sciences, Public health, Jakarta, Indonesia
3Osaka University, Graduate School of Engineering, Division of Sustainable Energy and Environmental Engineering, Osaka, Japan
*Corresponding author: narilamutia[at]uinjkt.ac.id
Abstract
Dengue Hemorrhagic Fever (DHF) is continued to be a burden of disease in Indonesia, particularly in Jakarta region. The change of climate condition is one factor that affect the occurrence of DHF. The objective of this study is to develop a dynamic model, estimate the cases of DHF using climate factor and calculate the burden of DHF utilizing single measure outcome, Disability Adjusted Life Year (DALY) in Jakarta. The actual data of temperature, relative humidity, rainfall and DHF cases from January 2000 to December 2013 were analyzed. We projected the DHF Incidences until 2050 using those climate factors by developing a dynamic model. We then calculate the burden of disease for DHF. Our result shows that relative humidity is climate factore which has the significant association with the DHF cases. In our model, the incidence rate of DHF is projecting to decrease until 2050. However, the burden of disease in the terms of DALY remains high in the period. It is expected that the model can assist the risk management for the DHF prevention from the environmental perspective. It is also possible to apply the model for measuring the burden of disease related to climate factor in other location.
Keywords
Climate change, health security, burden of disease, dengue, DALY
Topic
Biomedical and Health Technology
Corresponding Author
Ike Rahmawaty Alie
Institutions
Faculty of Medicine
Unisba
Abstract
Endothelial Dysfunction is defined as an imbalance between coagulation and thrombosis factors, loss of vasodilatation response ability in endothelium-dependent stimuli, loss of bioavailability of NO, increase in vasoconstrictive agents, interference with inflammatory regulation, and stimulate the release of microparticles. This was could be a risk on cardiovascular disease in the future. The purpose of this study was to analyze endothelial dysfunction earlier by releasing micro particles as potential biomarker cardiovascular risk on children and adult. The method in this study was reviewing articles using micro particles to detect endothelial dysfunction. Many studies from articles found that CD 31+ as one of micro particles biomarker increased in endothelial dysfunction. Microparticles could be released from endothel when the endothel got activation or apoptosis, this was especially chronic inflammatory that could be found on children such as obstructive sleep apnea or on adults such as obesity and many hypoxia conditions. This hypoxia causes endothelial stress which in turn causes apoptosis that can be a danger signal of acute ischemia and the incidence of hypoxia and triggers tissue repair mechanism.
Keywords
Cardiovascular, CD31+, Chronic Inflammation, Endothelial Dysfunction, Hypoxia
Topic
Biomedical and Health Technology
Corresponding Author
Irma Palupi
Institutions
a) School of Computing, Telkom University
Jl.Telekomunikasi No.1, Kabupaten Bandung.
Abstract
We model the growth of tumor cell in the microscopic point of view by using logistic type of Ordinary Differential Equation. Our model consider proliferative and quiescence type of cell including what we call angiogenic capacity. The parameters of the model will be adjusted by comparing to the experimental data of Ehrlich and fibrosarcoma Sa-37. After obtaining a relevant model, we develop a numerical scheme to simulate effectiveness of chemotherapy drugs to block or to kill proliferative of Tumor cell population.
Keywords
Chemotheraphy respon, Tumor population growth kinetics, Ehrlich and fibrosarcoma Sa-37
Topic
Biomedical and Health Technology
Corresponding Author
Fajar Awalia Yulianto
Institutions
(a) Department of Public Health, Faculty of Medicine Unisba
*fajar[at]unisba.ac.id
(b) Department of Biochemistry, Faculty of Medicine Unisba
Abstract
The escalating prevalence of metabolic diseases needs effective screening as a preventive strategy. Many tools are used to measure various metabolic parameters, both for research and clinical purposes. However, there is still doubt about the tools- reliability especially the digital type. This research aims to asses a Body Index Analyzer reliability that available in the market for calculating body composition consisted of body fat, visceral fat and skeletal muscle. There were 89 respondents that measured twice by two same brand and easy to find, digital body scales. The Bland-Altman plot was used to assess the body composition measurement reliability. Mean difference of body fat was 0.33 (95% CI -0.34 to 0.99), visceral fat was 0.53 (95% CI -0.37 to 1.45) and skeletal muscle was 0.01 (95% CI -0.11 to 0.13). Among those three parameters, the instrument has the most precise agreement in skeletal muscle measurement, although it still can be used to quantify body fat and visceral fat as well.
Keywords
bioimpedance analyzer, body composition, digital scale, reliability
Topic
Biomedical and Health Technology
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